Start new model of early childhood education

Start new model of early childhood education, Yesterday came into force a new educational model in more than 500 child development centers (CENDIS) and Community Child Care (CAIC) Mexico City, benefiting over 30 000 children.

"It's an alternative proposal (which) develops more play; you approach differently to the science building on children's curiosity, you approach differently and enter the word group dynamics," said Education Secretary capital, Mario Delgado.

In order to exploit the ability of children to play in this way to have fun while learning more than two thousand teachers will implement the so-called Comprehensive Alternative Proposal and Pre-School Education, Government of the Federal District.

"Today more than ever convinced of the need to think of schools as the best environment for the development of intelligence, emotions, creativity, democracy, science and art," says the Secretariat Education in the book of the project.

In the presence of the rector of the National Pedagogical University, Sylvia Ortega, and coordinating the development of the Proposed Alternative Comprehensive Education and Pre-School, Garduño Teresita Rubio Delgado Carrillo recalled that one of the key objectives is to generate to meet community among the children for a healthy living.

Also considered is a dialogue from a curriculum designed from the field of skills development that can guide teachers and figures cooperative work in coordination with the mothers and fathers of children who go to these centers.

The theoretical framework of the educational proposal states: "the thought is built on the direct action on the real. Intelligence is a product of interaction with others and others that form the environment of each subject. " The training is based on the symbol on the child, Jean Piaget.

Objectives

• Teaching children to have relationships governed by values ​​that contribute to reducing violence.
• Raising awareness of the fundamental role of children in the ecological balance of the city, country and world.
• Taking responsibility for one's own personal health and social participation in health.
• Building new literary languages, plastics, and cyber theater.

Read more

European Drivers Prefer Black Cars

European drivers prefer black cars, 25 percent of European car buyers opt for the color black, according to DuPont's annual report on trends in automotive color, 2011 (Global Automotive Colour Popularity Report). DuPont's study indicates that black color preference rose to 40 percent in the case of cars and luxury SUVs and confirms that this trend color launched in 2007 will continue in the coming years.

The target is following close
The second color used in European vehicles is white and white pearl, which maintains a 20 percent share, representing an increase of five percentage points compared with figures for the previous year's study.

The Color Marketing Manager for DuPont Refinish the Europe, Middle East and Asia, Ann Clerk, explained that the white represents increasingly modern minimalism and future technology, "and is an inspiration for the mega eco-trend in Europe. "

The silver falls in Europe
The silver, which was so fashionable in the early years of the second millennium is still the favorite of 15 percent of car buyers, passed with 18 percent gray.

The other colors do not exist
The other colors has little or nothing to do with the predominance of black and white. The blue hue is the fifth most popular European vehicles, with a penetration rate of 7 percent, followed by red, with a 6 per cent, and brown / beige, with 5 percent of the total, and green with only 1 percent.

And in the world challenge
The data in this report indicate that white is black and the colors are more popular vehicles around the world.

The color can vary the price of insurance

When choosing the color of the car the buyer almost never notices that may vary the price of your policy, but not all insurers use this type of scale.

Matter of visibility
The variation is not so much the price of the painting, very similar in all the variety of colors since the introduction of the foil as standard but in matters of visibility of the vehicle.

In general, light colors provide greater visibility to the vehicle, contrary to what happens with the darker colors. And on the road we must take into account that the greater visibility, reduced risk of accident.

The little black is
According to a study by the University of Auckland, New Zealand, the color of the vehicle determines the visibility of other drivers offer circulating around us. Thus, vehicles are more prone to accidents are, in order, brown, black and green.

Gray, the safest
On the opposite side of the scale are gray vehicles, which are the least likely to be involved in an accident. Apparently, and according to the study, the silver tint reduces up to 50 percent the risk of having an accident when compared with cars painted white, blue or red.

Read more

Discovery of a new mechanism of tumor cell reprogramming

Discovery of a new mechanism of tumor cell reprogramming, The journal Nature Medicine published a groundbreaking study on a protein that regulates the expression of hundreds of genes with a crucial role in the progression of pancreatic cancer, gliomas and possibly many other types of tumors. The study, conducted by researchers Raúl Méndez, a professor at the Institute for Research in Biomedicine (IRB Barcelona ICREA) and Pilar Navarro IMIM (Institut de Recerca Hospital del Mar in Barcelona), describes a new mechanism for the expression reprogramming of genes responsible for turning a healthy cell into a tumor cell, scientists have identified a protein CPEB4 "leader cells" that activates hundreds of genes associated with tumor growth.

"The peculiarity is that it is not only a specific gene mutation which promotes tumor growth, but also the expression of a protein in a wrong place, which would produce hundreds of messenger molecules that transmit genetic information, for the synthesis of proteins - without these genes mutate. This process leads to the expression of many normal genes, but in inadequate amounts, is more akin to the early stages of embryonic development to stages of development of adult organs, "said Raul Mendez, an expert in the CPEB protein family. Elena Ortiz-Zapater, lead author and Pilar Navarro clarified that "this is the case of tPA (tissue plasminogen activator), a protein normally not found in the healthy pancreas, but shows high expression in tumors of the pancreas. "

Discovery of a new mechanism of tumor cell reprogramming
One of the conclusions highlighted in the study is that in the tissues examined, pancreas and brain, CPEB4 not detected in healthy cells, only in tumors. Therefore, the inhibition of this protein would have an anti-tumor effect and few adverse effects.

Experiments with human cancer cells in mice, researchers have shown that lowering CPEB4 levels in cancer cells reduces tumor size by up to 80%. Although the study was limited to two types of tumor, according to the authors, "because of the effects observed in the tumors examined and the type of genes regulated by this mechanism is expected to be involved in many other cancers."

Discovery of a new mechanism of tumor cell reprogramming
This study opens new avenues for developing new treatments for cancer, so researchers are designing and analyzing CPEB4 inhibitors of potential therapeutic interest. "The clinical applications are very promising, but requires intensive research to identify inhibitory molecules and testing them in several models before determining its potential clinical use in patients," Mendez Navarro warned.

Read more